International Centers for Excellence in Malaria Research (ICEMR)
This is the fifth year of a seven year NIH funded research project under the Johns Hopkins School of Public Health to use Macha Research Trust as the center for a broadened understanding of the epidemiology, entomology and immunology of malaria. It is one of 10 such centers funded in the world. Two new field sites have been added to the one at MRT, one in Nchelenge District of Luapula Province of Zambia and one in Mutasa District of Eastern Zimbabwe to carry out the necessary field work. It is hoped that once baseline data is collected, using the same methodology used at Macha malaria in these two new sites can be controlled. Extensive state-of-the-art lab work is done in the molecular biology lab at Macha as part of this project, both on mosquitoes as well as on blood samples from people found to have malaria.
This special greenhouse-like building for mosquitoes was funded by Hopkins in 2013, and was completed in 2014 with an official opening on March 4th, 2014. It is a unique facility (one of about 12 in the world and the only one in southern Africa) in which large scale experiments can be done to better understand mosquito behavior and investigate possible ways to manipulate their environment to control malaria transmission.\r\nClearance of malaria parasites after artemisinin-combination therapy. This small special project is being carried out in Nchelenge, Zambia and will enroll 90 children with malaria and document how long it takes for them to clear the parasites after treatment. The aim is to document whether any malaria parasites in Zambia are showing evidence of early resistance to these drugs.